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Volume 358:2832-2837 June 26, 2008 Number 26
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Informing Candidates for Solid-Organ Transplantation about Donor Risk Factors
Scott D. Halpern, M.D., Ph.D., Abraham Shaked, M.D., Ph.D., Richard D. Hasz, M.F.S., and Arthur L. Caplan, Ph.D.

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-PubMed Citation
For the first time in 15 years, there has been documented transmission of the human immunodeficiency virus (HIV) through solid-organ transplantation.1 Although transmission of infectious agents through transplantation is rare,2 such cases raise important questions about how informed consent for transplantation should be obtained and about the type of resource that transplantable organs represent.

Among the questions raised are the following: Should potential recipients be informed about the general risks associated with transplantation or those specifically associated with an identified organ? Should the risks engendered by the behavior of donors be treated differently from those associated with the medical profiles . . . [Full Text of this Article]

The Chicago Case

Behavioral Risks among Donors

Behavioral versus Medical Donor Risks

Models of Disclosure of Risks

The Right to Prospectively Decline Nonstandard Organs

Ensuring Equity

Conclusions


Source Information

From the Pulmonary, Allergy, and Critical Care Division (S.D.H.), Center for Bioethics (S.D.H., A.L.C.), Leonard Davis Institute of Health Economics (S.D.H., A.L.C.), Center for Clinical Epidemiology and Biostatistics (S.D.H.), and Penn Transplant Institute (A.S.), University of Pennsylvania School of Medicine; and the Gift of Life Donor Program (R.D.H.) — both in Philadelphia.



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