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Clinical Implications of Basic Research
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Volume 351:827-828 August 19, 2004 Number 8
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A Candidate Vaccine for Severe Acute Respiratory Syndrome
Robert E. Johnston, Ph.D.

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The story of the epidemic of severe acute respiratory syndrome (SARS) is a frightening one in many respects, but it provides heartening news about our ability to respond to an emergency. Less than 18 months after the first alerts of the disease were issued,1 the causative virus has been isolated,2 and Yang and colleagues have recently reported the efficacy of a prototype vaccine in a mouse model of infection.3 This advance was built on the back of a great deal of basic research4,5 and thus underscores the wisdom of asking questions that are not necessarily geared toward known pathogens in . . . [Full Text of this Article]


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From the Carolina Vaccine Institute, University of North Carolina, Chapel Hill.


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