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A 45-year-old man was admitted to this hospital for orthotopic liver transplantation. The patient had been well until the age of 18 years, when a diagnosis of non-A, non-B hepatitis was made after a 1-month episode of jaundice; the source of exposure was thought to be tattoos. Jaundice recurred intermittently thereafter. Six years before admission, the episodes became more frequent and severe, and chronic pruritus developed. Serologic testing disclosed antibodies to hepatitis C virus (HCV) and hepatitis B virus (HBV) core and surface antigens; tests for hepatitis B surface antigen and antibodies to hepatitis A were negative. The patient began
Differential Diagnosis
Causes of Mental-Status Changes after Liver Transplantation
Risk Factors for Infection in Allograft Recipients
Infection in the Early Post-Transplantation Period
Reactivation of Infection in the Recipient
Donor-Derived Infections
CNS Infections
Invasive Fungal Infection and Cryptococcal Meningitis
Clinical Diagnosis
Dr. Jay A. Fishman's Diagnosis
Pathological Discussion
Discussion of Management
Anatomical Diagnosis
Source Information
From the Massachusetts General Hospital Transplant Center (J.A.F.); the Transplant Infectious Disease and Compromised Host Program (J.A.F.) and the Departments of Radiology (R.G.G.) and Pathology (J.A.B.), Massachusetts General Hospital; and the Departments of Medicine (J.A.F.), Radiology (R.G.G.), and Pathology (J.A.B.), Harvard Medical School — all in Boston.
Related Letters:
Case 11-2008: Mental-Status Changes after Liver Transplantation
Antinori S., Corbellino M., Joy M., Fishman J. A., Gonzalez R. G.
Extract |
Full Text |
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N Engl J Med 2008;
359:207-209, Jul 10, 2008.
Correspondence
This article has been cited by other articles:
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