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Previous Volume 359:715-721 August 14, 2008 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author's clinical recommendations.

A 44-year-old businessman with a history of hypertension presents for evaluation with a report of being under stress at work and home, which has led to "unsatisfactory" sleep. Although there is some despondency, screening for depression is negative. His . . . [Full Text of this Article]

The Clinical Problem

Pathophysiology and Effect of Therapy

Clinical Evidence

Clinical Use

Adverse Effects

Areas of Uncertainty

Guidelines

Recommendations

Source Information

From the Center for Drug and Alcohol Programs and the Charleston Alcohol Research Center, Medical University of South Carolina, Charleston.

Address reprint requests to Dr. Anton at the Charleston Alcohol Research Center, Medical University of South Carolina, 67 President St., P.O. Box-MSC861 250861, Charleston, SC 29425, or at antonr@musc.edu.

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