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Volume 359:891-893 August 28, 2008 Number 9
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The Power of the Extreme in Elucidating Obesity
Philippe Froguel, M.D., Ph.D., and Alexandra I.F. Blakemore, Ph.D.

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 by Han, J. C.
-PubMed Citation
Despite the worrisome statistics that 16% of children in the United States are obese and that the number of adults with a body-mass index (the weight in kilograms divided by the square of the height in meters) of 50 or more has increased by a factor of 6 in the past 10 years, no simple environmental explanation for the obesity epidemic has proved valid. Many health advisers view obesity simply as a reflection of unwise personal lifestyle choices, and many would probably be surprised to learn that adiposity is one of the most heritable of human traits. Data from recent . . . [Full Text of this Article]


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Dr. Froguel is chair of the Department of Genomic Medicine, Hammersmith Hospital, Imperial College London, London; Dr. Blakemore is a senior lecturer at the same institution.




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