Acute kidney injury is associated with morbidity and mortalityrates of more than 50% in critically ill patients, despite thepotential for recovery of renal function and many advances inmedical management.1 To manage the care of patients with acutekidney injury, we must optimize their hemodynamic and volumestatus, correct metabolic abnormalities, provide adequate nutrition,and minimize progression of injury. Dialysis is often required,and critical factors to consider when designing a dialysis strategyfor patients with acute kidney injury are determining the extentof dialysis and fluid removal, determining when to start dialysis,and selecting the most appropriate . . . [Full Text of this Article]
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From the Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston.
This article (10.1056/NEJMe0803765) was published at www.nejm.org on May 20, 2008. It will appear in the July 3 issue of the Journal.
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